Across TCGA patient cohorts, MRPL23 protein abundance is significantly associated with the RNA expression of many other genes, with 12,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL23-associated genes across cancer lineages are ERMN, LCP1, and GNG2. Each is linked with MRPL23 in more than 5 cancer types. Because this analysis shows association rather than direction, both MRPL23-to-partner and partner-to-MRPL23 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL23→partner) and Y-score (partner→MRPL23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ERMN →	-1.693	-0.229	<.001	.001	3	6
COAD	LCP1 →	-0.933	-0.505	<.001	<.001	3	5
COAD	GNG2 →	-0.679	-0.424	<.001	<.001	3	5
COAD	RASSF2 →	-0.754	-0.483	<.001	<.001	3	5
GBM	PPP1R16B →	-1.068	-0.185	.001	.007	3	5
COAD	GYPC →	-0.924	-0.459	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,933 associations by consensus.

Exploration

MRPL23 survival (RNA) · tumor vs normal (RNA) · all MRPL23 data types