MRPL22

Across TCGA patient cohorts, MRPL22 protein abundance is significantly associated with the RNA expression of many other genes, with 17,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL22-associated genes across cancer lineages are STARD9, COX7A1, and NEXN. Each is linked with MRPL22 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL22-to-partner and partner-to-MRPL22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL22 versus STARD9 in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL22→partner) and Y-score (partner→MRPL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STARD9 →	-0.834	-0.340	<.001	<.001	3	7
CCRCC	COX7A1 →	-0.984	-0.257	.002	<.001	3	7
HNSC	NEXN →	-0.979	-0.171	<.001	.003	3	7
COAD	LYL1 →	-0.578	-0.308	<.001	<.001	3	6
UCEC	C7 →	-1.576	-0.260	<.001	<.001	3	6
UCEC	TCF21 →	-0.578	-0.321	.006	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,131 associations by consensus.

MRPL22 vs STARD9 — UCEC

Explore this scatter interactively →