MRPL20

Across TCGA pan-cancer cohorts, MRPL20 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MRPL20 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPL20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPL20 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LUAD, and LSCC are the cancer types where MRPL20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.925	.047	12	view →
LUAD	DFS	Median	All	0.491	0.931	.002	12	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.689	.002	11	view →
PDAC	DFS	Tertile	All	0.496	0.323	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MRPL20–COAD (DFS)

Open the COAD breakdown →