MRPL17

Across TCGA pan-cancer cohorts, MRPL17 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MRPL17 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPL17 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPL17 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and UCEC are the cancer types where MRPL17 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.899	.028	18	view →
LSCC	OS	Median	All	1.000	0.925	.017	9	view →
UCEC	OS	Quartile	II,III,IV	0.386	1.000	.012	8	view →
LUAD	DFS	Tertile	II,III,IV	0.370	1.000	.018	7	view →
HNSC	OS	Tertile	All	0.762	0.912	.006	6	view →
GBM	OS	Median	All	0.448	0.300	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MRPL17–COAD (DFS)

Open the COAD breakdown →