MRPL17

Across TCGA patient cohorts, MRPL17 protein abundance is significantly associated with the RNA expression of many other genes, with 15,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL17-associated genes across cancer lineages are MT-CO2, PDE1B, and VSTM4. Each is linked with MRPL17 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL17-to-partner and partner-to-MRPL17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL17 versus MT-CO2 in HNSC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL17→partner) and Y-score (partner→MRPL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT-CO2 →	+0.718	+0.222	.005	.002	3	7
UCEC	PDE1B →	-0.546	-0.351	.007	.001	3	6
LSCC	VSTM4 →	-0.764	-0.423	<.001	<.001	3	6
UCEC	TNFSF12 →	-0.709	-0.371	.002	<.001	2	7
BRCA	MEOX2 →	-1.111	-0.468	<.001	<.001	3	6
BRCA	CNRIP1 →	-0.748	-0.273	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,068 associations by consensus.

MRPL17 vs MT-CO2 — HNSC

Explore this scatter interactively →