MRPL14

Across TCGA patient cohorts, MRPL14 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL14-associated genes across cancer lineages are MIR7702, IGHV4-4, and IGHV3OR16-9. Each is linked with MRPL14 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL14-to-partner and partner-to-MRPL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by MRPL14-low versus MRPL14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL14→partner) and Y-score (partner→MRPL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.469	+5.475	<.001	.001	3	1
UCEC	IGHV4-4 →	+1.273	+2.953	.001	.007	3	1
UCEC	IGHV3OR16-9 →	+0.731	+3.001	.003	.006	3	1
COAD	RNU6-501P →	+0.464	+4.602	<.001	.008	3	1
COAD	RNU6-932P →	+0.432	+4.790	<.001	.006	3	1
COAD	GACAT1 →	+0.157	+5.917	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

MIR7702 by MRPL14 expression — UCEC

Explore this box plot interactively →