MRPL14

Across TCGA cell cohorts, MRPL14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,727 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL14-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, DNA replication initiation, and Positive regulation of G2/MI transition of meiotic cell cycle. Each is linked with MRPL14 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPL14-to-partner and partner-to-MRPL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by MRPL14-low versus MRPL14-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL14→partner) and Y-score (partner→MRPL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.105	+0.508	<.001	<.001	3	13
BLOOD_Myeloma	DNA replication initiation →	+0.166	+0.941	<.001	<.001	3	11
PANCREAS	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.080	+0.517	.001	<.001	3	9
PANCREAS	Regulation of mitotic sister chromatid segregation →	+0.094	+0.683	.004	<.001	3	9
PANCREAS	Dihydrofolate metabolic process →	+0.120	+0.580	<.001	<.001	3	9
BLOOD_Lymphoma	Regulation of nuclear division →	+0.055	+0.444	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,727 associations by consensus.

Protein peptidyl-prolyl isomerization by MRPL14 expression — PANCREAS

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