MRPL13

Across TCGA cell cohorts, MRPL13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,698 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MRPL13-associated GO terms across cancer lineages are Protein localization to kinetochore, Protein localization to condensed chromosome, and Meiotic spindle assembly. Each is linked with MRPL13 in more than 18 cancer types. Because this analysis shows association rather than direction, both MRPL13-to-partner and partner-to-MRPL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by MRPL13-low versus MRPL13-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL13→partner) and Y-score (partner→MRPL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein localization to kinetochore →	+0.146	+0.756	.001	.003	2	19
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.166	+1.327	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Meiotic spindle assembly →	+0.110	+0.790	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Protein localization to chromosome, centromeric region →	+0.132	+0.987	<.001	<.001	2	15
LUNG_NSCLC_LUSC	Mitotic sister chromatid cohesion →	+0.112	+0.782	<.001	.003	3	12
BLOOD_Lymphoma	Response to forskolin →	-0.131	-0.606	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,698 associations by consensus.

Protein localization to kinetochore by MRPL13 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →