MRPL11

Across TCGA patient cohorts, MRPL11 protein abundance is significantly associated with the RNA expression of many other genes, with 16,866 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL11-associated genes across cancer lineages are NEXN, CDC42EP3, and MAGI2-AS3. Each is linked with MRPL11 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL11-to-partner and partner-to-MRPL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL11 versus NEXN in BRCA, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL11→partner) and Y-score (partner→MRPL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NEXN →	-1.045	-0.321	<.001	<.001	3	7
BRCA	CDC42EP3 →	-0.969	-0.344	<.001	<.001	3	7
OV	MAGI2-AS3 →	-1.005	-0.384	<.001	<.001	3	7
LSCC	MFNG →	-0.639	-0.301	<.001	<.001	3	6
OV	JCAD →	-1.000	-0.369	.002	.001	3	6
BRCA	MSRB3 →	-1.149	-0.283	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,866 associations by consensus.

MRPL11 vs NEXN — BRCA

Explore this scatter interactively →