MRPL11

Across TCGA cell cohorts, MRPL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,896 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL11-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Mitotic DNA replication, and Cell cycle DNA replication. Each is linked with MRPL11 in more than 16 cancer types. Because this analysis shows association rather than direction, both MRPL11-to-partner and partner-to-MRPL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by MRPL11-low versus MRPL11-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL11→partner) and Y-score (partner→MRPL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA replication checkpoint signaling →	+0.154	+0.834	.003	.008	2	17
PANCREAS	Mitotic DNA replication →	+0.187	+0.623	.001	<.001	3	16
BONE	Cell cycle DNA replication →	+0.178	+0.817	.006	.003	3	16
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.197	+1.350	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.194	+1.152	.002	.001	2	16
PANCREAS	Mitotic metaphase chromosome alignment →	+0.084	+0.648	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,896 associations by consensus.

DNA replication checkpoint signaling by MRPL11 expression — LIVER

Explore this box plot interactively →