MRPL10

Across TCGA patient cohorts, MRPL10 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL10-associated genes across cancer lineages are CD8+ naive T-cells, Memory B-cells, and mv Endothelial cells. Each is linked with MRPL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL10-to-partner and partner-to-MRPL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by MRPL10-low versus MRPL10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL10→partner) and Y-score (partner→MRPL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.032	+3.502	.016	.002	3	1
UCEC	Memory B-cells →	+0.029	+1.860	.033	.044	3	1
UCEC	mv Endothelial cells →	-0.032	-2.311	.006	.036	3	1
UCEC	Erythrocytes →	+0.049	+2.321	<.001	.036	1	1
UCEC	lymphatic Endothelial cells →	-0.025	-2.268	.039	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ naive T-cells by MRPL10 expression — UCEC

Explore this box plot interactively →