MRPL1

Across TCGA cell cohorts, MRPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,669 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL1-associated GO terms across cancer lineages are Protein localization to kinetochore, DAMP biosynthetic process, and Purine deoxyribonucleoside monophosphate biosynthetic process. Each is linked with MRPL1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRPL1-to-partner and partner-to-MRPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by MRPL1-low versus MRPL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL1→partner) and Y-score (partner→MRPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.116	+0.815	<.001	<.001	3	16
STOMACH	DAMP biosynthetic process →	+0.178	+0.887	<.001	<.001	3	16
STOMACH	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.178	+0.887	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Spermidine biosynthetic process →	+0.172	+1.038	.001	<.001	3	15
LUNG_NSCLC_LUSC	U1 snRNA 3'-end processing →	+0.116	+0.524	.004	.004	2	15
LUNG_NSCLC_LUSC	U5 snRNA 3'-end processing →	+0.116	+0.524	.004	.004	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,669 associations by consensus.

Protein localization to kinetochore by MRPL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →