MROH8

Across TCGA patient cohorts, MROH8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,375 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MROH8-associated proteins across cancer lineages are HDGFL3, CRYBG1, and S100A12. Each is linked with MROH8 in more than 4 cancer types. Because this analysis shows association rather than direction, both MROH8-to-partner and partner-to-MROH8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MROH8 versus HDGFL3 in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MROH8→partner) and Y-score (partner→MROH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.754	+0.466	<.001	<.001	3	5
BRCA	CRYBG1 →	-0.712	-0.461	<.001	<.001	3	4
GBM	S100A12 →	-1.046	-0.366	.008	.009	2	5
BRCA	CRTC1 →	+0.288	+0.341	.002	.002	3	4
OV	DPYSL2 →	+0.637	+0.491	.004	.004	3	4
PDAC	ERO1A →	-0.502	-0.180	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,375 associations by consensus.

MROH8 vs HDGFL3 — BRCA

Explore this scatter interactively →