MROH8

Across TCGA cell cohorts, MROH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,548 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MROH8-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Cell division, and Regulation of cell cycle G1/S phase transition. Each is linked with MROH8 in more than 8 cancer types. Because this analysis shows association rather than direction, both MROH8-to-partner and partner-to-MROH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by MROH8-low versus MROH8-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MROH8→partner) and Y-score (partner→MROH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.073	+0.912	<.001	<.001	3	9
BLOOD_Leukemia	Cell division →	+0.063	+1.120	<.001	<.001	3	8
LUNG_SCLC	Regulation of cell cycle G1/S phase transition →	+0.072	+1.006	<.001	<.001	3	8
BREAST	Positive regulation of double-strand break repair →	+0.067	+0.745	<.001	<.001	2	9
BLOOD_Leukemia	DNA replication →	+0.048	+0.716	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.080	+0.450	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,548 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by MROH8 expression — LUNG_SCLC

Explore this box plot interactively →