MROH6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MROH6 mutation is significantly associated with the RNA expression of many other genes, with 769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MROH6-associated genes across cancer lineages are RN7SL402P, MIR549A, and RNA5SP247. Each is linked with MROH6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MROH6-to-partner and partner-to-MROH6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MROH6→partner) and Y-score (partner→MROH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL402P →+0.233+4.236<.001.00132
CESCMIR549A →+0.247+4.342<.001.00732
UCECRNA5SP247 →+0.404+1.816<.001.00332
UCECDDX43P3 →+0.366+1.725<.001.00632
UCECRN7SL513P →+0.241+1.928.004.00532
UCECRNU7-81P →+0.267+2.868<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 769 associations by consensus.

Exploration