Across TCGA cell cohorts, MROH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,387 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MROH6-associated GO terms across cancer lineages are Negative regulation of hippocampal neuron apoptotic process, Response to kainic acid, and Positive regulation of fat cell differentiation. Each is linked with MROH6 in more than 9 cancer types. Because this analysis shows association rather than direction, both MROH6-to-partner and partner-to-MROH6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MROH6→partner) and Y-score (partner→MROH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of hippocampal neuron apoptotic process →	+1.269	+1.428	<.001	.002	3	10
LUNG_SCLC	Response to kainic acid →	+0.131	+0.774	.004	.007	3	10
LUNG_NSCLC_LUAD	Positive regulation of fat cell differentiation →	+0.057	+1.445	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Establishment of epithelial cell apical/basal polarity →	-0.178	-2.050	<.001	<.001	3	9
BONE	Negative regulation of translational initiation →	+0.113	+0.962	<.001	.005	3	9
PANCREAS	Regulation of tumor necrosis factor (ligand) superfamily member 11 production →	+1.595	+2.266	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,387 associations by consensus.

Exploration

MROH6 survival (RNA) · tumor vs normal (RNA) · all MROH6 data types