MROH4P

Across TCGA pan-cancer cohorts, MROH4P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MROH4P data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher MROH4P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MROH4P expression acts as an unfavorable survival marker, although some lineages such as HNSC and LIHC show a favorable association.

PAAD, KICH, and UCEC are the cancer types where MROH4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.168	0.619	<.001	81	view →
KICH	OS	Tertile	All	0.161	0.881	<.001	72	view →
UCEC	OS	Tertile	All	0.874	0.927	.004	48	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	45	view →
UVM	DFS	Tertile	All	0.213	0.761	.017	36	view →
LAML	DFS	Tertile	All	0.187	0.522	.003	28	view →
THYM	OS	Tertile	All	0.778	0.983	.001	24	view →
KIRP	DFS	Tertile	III,IV	0.261	0.742	.005	21	view →
BLCA	OS	Tertile	IV	0.247	0.602	.040	18	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
THCA	DFS	Tertile	II,III,IV	0.145	0.794	.001	18	view →
HNSC	OS	Tertile	II,III,IV	0.607	0.374	.042	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MROH4P–PAAD (OS)

Open the PAAD breakdown →