MROH1

Across TCGA pan-cancer cohorts, MROH1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MROH1 data layer compared with 27 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MROH1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MROH1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where MROH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.936	0.770	.009	24	view →
PDAC	DFS	Tertile	All	0.632	0.931	.005	19	view →
CCRCC	OS	Tertile	IV	0.177	1.000	.036	12	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.909	.046	6	view →
LUAD	OS	Median	III,IV	0.861	0.395	.002	5	view →
GBM	DFS	Quartile	All	0.205	0.548	.012	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MROH1–UCEC (DFS)

Open the UCEC breakdown →