MRNIP

Across TCGA pan-cancer cohorts, MRNIP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MRNIP data layer compared with 28 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MRNIP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MRNIP expression acts as an unfavorable survival marker.

BLCA, ESCA, and KIRP are the cancer types where MRNIP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.153	0.720	<.001	33	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →
KIRP	OS	Median	All	0.192	0.705	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MRNIP–BLCA (OS)

Open the BLCA breakdown →