MRNIP

Across TCGA patient cohorts, MRNIP protein abundance is significantly associated with the RNA expression of many other genes, with 12,543 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MRNIP-associated genes across cancer lineages are CLK4, CEP120, and RUFY1. Each is linked with MRNIP in more than 4 cancer types. Because this analysis shows association rather than direction, both MRNIP-to-partner and partner-to-MRNIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRNIP versus CLK4 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRNIP→partner) and Y-score (partner→MRNIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CLK4 →	+0.985	+0.611	.001	<.001	3	5
BRCA	CEP120 →	+0.388	+0.290	<.001	<.001	3	5
BRCA	RUFY1 →	+0.574	+0.412	<.001	<.001	3	5
OV	BRD8 →	+0.962	+0.502	.001	.002	3	4
UCEC	IK →	+0.817	+0.348	<.001	<.001	3	4
BRCA	CREBRF →	+0.459	+0.306	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,543 associations by consensus.

MRNIP vs CLK4 — OV

Explore this scatter interactively →