MRM3

Across TCGA patient cohorts, MRM3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,885 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRM3-associated genes across cancer lineages are TMEM119, ISLR, and VGLL3. Each is linked with MRM3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRM3-to-partner and partner-to-MRM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRM3 versus TMEM119 in BRCA, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRM3→partner) and Y-score (partner→MRM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM119 →	-0.981	-0.287	<.001	<.001	3	7
OV	ISLR →	-1.509	-0.580	<.001	<.001	3	7
LSCC	VGLL3 →	-0.932	-0.402	<.001	<.001	3	7
BRCA	LYL1 →	-0.669	-0.393	<.001	<.001	3	6
COAD	CXCL12 →	-1.189	-0.305	<.001	.001	3	6
OV	CNRIP1 →	-0.830	-0.606	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,885 associations by consensus.

MRM3 vs TMEM119 — BRCA

Explore this scatter interactively →