MRM1

Across TCGA cell cohorts, MRM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,464 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRM1-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA metabolic process, and Maturation of 5.8S rRNA. Each is linked with MRM1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRM1-to-partner and partner-to-MRM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by MRM1-low versus MRM1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRM1→partner) and Y-score (partner→MRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.070	+0.779	<.001	<.001	3	14
LUNG_SCLC	rRNA metabolic process →	+0.097	+0.935	<.001	<.001	3	13
BONE	Maturation of 5.8S rRNA →	+0.122	+0.927	.008	.003	2	14
LUNG_SCLC	Mitochondrial tRNA pseudouridine synthesis →	+0.138	+1.072	<.001	.001	3	12
LUNG_SCLC	rRNA modification →	+0.084	+0.717	<.001	<.001	3	12
LUNG_SCLC	Nucleolar large rRNA transcription by RNA polymerase I →	+0.113	+0.756	.002	.008	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,464 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by MRM1 expression — BLOOD_Lymphoma

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