MRI1

Across TCGA cell cohorts, MRI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,351 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MRI1-associated GO terms across cancer lineages are L-methionine cycle, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Pre-mRNA catabolic process. Each is linked with MRI1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRI1-to-partner and partner-to-MRI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-methionine cycle grouped by MRI1-low versus MRI1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRI1→partner) and Y-score (partner→MRI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	L-methionine cycle →	+0.191	+1.190	<.001	<.001	3	16
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.197	+1.403	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.196	+0.845	<.001	<.001	3	13
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.221	+1.047	<.001	<.001	3	13
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.106	+1.176	<.001	<.001	3	12
BONE	Electron transport coupled proton transport →	+0.106	+1.176	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,351 associations by consensus.

L-methionine cycle by MRI1 expression — STOMACH

Explore this box plot interactively →