MRGPRX5P

Across TCGA patient cohorts, MRGPRX5P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,966 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRGPRX5P-associated GO terms across cancer lineages are Intrinsic apoptotic signaling pathway by p53 class mediator, Extrinsic apoptotic signaling pathway, and 'de novo' protein folding. Each is linked with MRGPRX5P in more than 6 cancer types. Because this analysis shows association rather than direction, both MRGPRX5P-to-partner and partner-to-MRGPRX5P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intrinsic apoptotic signaling pathway by p53 class mediator grouped by MRGPRX5P-low versus MRGPRX5P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRX5P→partner) and Y-score (partner→MRGPRX5P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.119	+0.036	<.001	<.001	3	7
STAD	Extrinsic apoptotic signaling pathway →	+0.120	+0.035	<.001	<.001	3	6
STAD	'de novo' protein folding →	+0.130	+0.037	<.001	<.001	3	6
STAD	Regulation of protein ubiquitination →	+0.126	+0.040	<.001	<.001	3	6
STAD	Positive regulation of protein ubiquitination →	+0.120	+0.044	<.001	<.001	3	6
STAD	Positive regulation of amide metabolic process →	+0.126	+0.036	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,966 associations by consensus.

Intrinsic apoptotic signaling pathway by p53 class mediator by MRGPRX5P expression — STAD

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