MRGPRX2

Across TCGA patient cohorts, MRGPRX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,903 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRGPRX2-associated GO terms across cancer lineages are Organelle disassembly, Vacuolar transport, and Cytosolic transport. Each is linked with MRGPRX2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MRGPRX2-to-partner and partner-to-MRGPRX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by MRGPRX2-low versus MRGPRX2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRX2→partner) and Y-score (partner→MRGPRX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Organelle disassembly →	+0.072	+0.056	<.001	<.001	3	15
STAD	Vacuolar transport →	+0.071	+0.058	<.001	<.001	3	15
STAD	Cytosolic transport →	+0.068	+0.062	<.001	<.001	3	15
STAD	Regulation of mRNA processing →	+0.077	+0.055	<.001	<.001	3	14
STAD	Biological process involved in interaction with symbiont →	+0.062	+0.059	<.001	<.001	3	14
STAD	Signal transduction by p53 class mediator →	+0.065	+0.058	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,903 associations by consensus.

Organelle disassembly by MRGPRX2 expression — STAD

Explore this box plot interactively →