Across TCGA pan-cancer cohorts, MRGPRX13P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MRGPRX13P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MRGPRX13P RNA is repressed in tumor relative to normal tissue. In most cancer types MRGPRX13P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA are the cancer types where MRGPRX13P tumor–normal differential expression is most reproducible.