MRGPRX12P

Across TCGA pan-cancer cohorts, MRGPRX12P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MRGPRX12P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRGPRX12P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRGPRX12P expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

COAD, UVM, and LGG are the cancer types where MRGPRX12P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.277	0.812	<.001	114	view →
UVM	OS	Tertile	All	0.104	0.858	<.001	99	view →
LGG	DFS	Tertile	All	0.418	0.830	<.001	27	view →
HNSC	DFS	Tertile	II,III,IV	0.172	0.558	.009	27	view →
LIHC	OS	Tertile	III,IV	0.072	0.626	<.001	27	view →
TGCT	OS	Tertile	All	0.771	0.968	.017	18	view →
READ	OS	Tertile	III,IV	0.287	0.747	.027	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
LUAD	OS	Tertile	III,IV	0.228	0.677	.015	9	view →
SARC	OS	Tertile	All	0.145	0.600	.002	9	view →
STAD	DFS	Tertile	All	0.552	0.675	.034	6	view →
MESO	OS	Tertile	IV	1.000	0.318	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MRGPRX12P–COAD (OS)

Open the COAD breakdown →