MRGBP

Across TCGA pan-cancer cohorts, MRGBP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MRGBP data layer compared with 30 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MRGBP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MRGBP expression acts as an unfavorable survival marker.

BLCA, KICH, and LIHC are the cancer types where MRGBP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.051	0.720	<.001	39	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
LIHC	OS	Median	All	0.008	0.777	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MRGBP–BLCA (OS)

Open the BLCA breakdown →