MRFAP1L1

Across TCGA patient cohorts, MRFAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRFAP1L1-associated genes across cancer lineages are RNA5SP482, RNU6-1138P, and RPS23P4. Each is linked with MRFAP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRFAP1L1-to-partner and partner-to-MRFAP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP482 grouped by MRFAP1L1-low versus MRFAP1L1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRFAP1L1→partner) and Y-score (partner→MRFAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP482 →	+0.247	+7.731	<.001	.009	3	2
COAD	RNU6-1138P →	+0.476	+5.790	<.001	.003	3	1
COAD	RPS23P4 →	+0.238	+5.145	<.001	.007	3	1
COAD	SNORD116-30 →	+0.556	+5.602	<.001	.004	3	1
COAD	MTND3P13 →	+0.221	+5.893	<.001	.002	3	1
COAD	MIR4710 →	+0.575	+5.602	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RNA5SP482 by MRFAP1L1 expression — BRCA

Explore this box plot interactively →