MRC1

Across TCGA patient cohorts, MRC1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,205 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRC1-associated genes across cancer lineages are LILRB5, CCL13, and CCL23. Each is linked with MRC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MRC1-to-partner and partner-to-MRC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRC1 versus LILRB5 in CCRCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRC1→partner) and Y-score (partner→MRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LILRB5 →	+1.164	+0.771	<.001	<.001	3	10
PDAC	CCL13 →	+2.203	+0.612	<.001	<.001	3	10
LSCC	CCL23 →	+1.149	+0.717	<.001	<.001	3	10
GBM	MS4A4A →	+1.458	+1.101	<.001	<.001	3	9
HNSC	ARHGAP9 →	+0.916	+0.586	<.001	<.001	3	9
GBM	F13A1 →	+2.341	+1.118	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,205 associations by consensus.

MRC1 vs LILRB5 — CCRCC

Explore this scatter interactively →