MRAP2

Across TCGA patient cohorts, MRAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRAP2-associated genes across cancer lineages are GRHL2, MASTL, and DPP4. Each is linked with MRAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MRAP2-to-partner and partner-to-MRAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRAP2 versus GRHL2 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRAP2→partner) and Y-score (partner→MRAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GRHL2 →	+1.245	+1.176	.004	<.001	3	4
GBM	MASTL →	+0.779	+0.767	.003	.007	3	3
UCEC	DPP4 →	-2.765	-1.281	.006	<.001	3	3
HNSC	HMGXB4 →	+0.755	+0.380	.009	.004	3	3
HNSC	SPRTN →	+0.558	+0.419	.005	<.001	3	3
GBM	EZH2 →	+1.274	+0.847	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,146 associations by consensus.

MRAP2 vs GRHL2 — UCEC

Explore this scatter interactively →