MRAP2

Across TCGA cell cohorts, MRAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,963 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MRAP2-associated GO terms across cancer lineages are Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway, Aerobic respiration, and Calcium ion transport. Each is linked with MRAP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRAP2-to-partner and partner-to-MRAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway grouped by MRAP2-low versus MRAP2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRAP2→partner) and Y-score (partner→MRAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.302	-0.821	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.100	+0.555	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Calcium ion transport →	-0.041	-0.462	.002	.005	3	7
LARGE_INTESTINE	Negative regulation of appetite by leptin-mediated signaling pathway →	+0.086	+0.965	.001	.001	3	7
LUNG_SCLC	Purine nucleoside triphosphate biosynthetic process →	+0.087	+1.753	.005	.009	3	7
LUNG_SCLC	Purine ribonucleoside triphosphate metabolic process →	+0.051	+1.395	.004	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,963 associations by consensus.

Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway by MRAP2 expression — BREAST

Explore this box plot interactively →