MRAP

Across TCGA patient cohorts, MRAP mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRAP-associated genes across cancer lineages are CD8+ Tem and NK cells. Each is linked with MRAP in more than 1 cancer types. Because this analysis shows association rather than direction, both MRAP-to-partner and partner-to-MRAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by MRAP-low versus MRAP-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRAP→partner) and Y-score (partner→MRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CD8+ Tem →	+0.013	+3.982	<.001	.014	3	1
STAD	NK cells →	+0.008	+5.012	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tem by MRAP expression — STAD

Explore this box plot interactively →