MPV17

Across TCGA cell cohorts, MPV17 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,794 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MPV17-associated GO terms across cancer lineages are Negative regulation of inflammatory response to wounding, Store-operated calcium entry, and Epidermal cell differentiation. Each is linked with MPV17 in more than 7 cancer types. Because this analysis shows association rather than direction, both MPV17-to-partner and partner-to-MPV17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of inflammatory response to wounding grouped by MPV17-low versus MPV17-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17→partner) and Y-score (partner→MPV17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of inflammatory response to wounding →	-0.127	-0.477	.009	.001	3	8
SKIN	Store-operated calcium entry →	+0.094	+0.525	.003	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Epidermal cell differentiation →	-0.140	-0.922	.003	.002	3	6
LIVER	Non-motile cilium assembly →	+0.077	+0.563	<.001	.003	3	6
STOMACH	Feeding behavior →	-0.166	-0.601	.002	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Intermediate filament organization →	-0.137	-0.564	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,794 associations by consensus.

Negative regulation of inflammatory response to wounding by MPV17 expression — SKIN

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