MPPED1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MPPED1 mutation is significantly associated with the RNA expression of many other genes, with 432 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPPED1-associated genes across cancer lineages are RNU1-129P, NDRG2, and IFRD1. Each is linked with MPPED1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MPPED1-to-partner and partner-to-MPPED1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPPED1→partner) and Y-score (partner→MPPED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU1-129P →+0.405+3.886.006.00833
UCECNDRG2 →-0.920-2.684.001.00632
UCECIFRD1 →+0.696+3.716<.001<.00132
SKCMLINC02509 →+0.325+5.328<.001.00332
HNSCRNU6-249P →+0.471+3.654<.001.00932
LUADTRIAP1P1 →+0.073+4.301<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 432 associations by consensus.

Exploration