MPPE1

Across TCGA patient cohorts, MPPE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible MPPE1-associated GO terms across cancer lineages are Protein localization to phagophore assembly site, GPI anchor metabolic process, and Golgi to plasma membrane transport. Each is linked with MPPE1 in more than 31 cancer types. Because this analysis shows association rather than direction, both MPPE1-to-partner and partner-to-MPPE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to phagophore assembly site grouped by MPPE1-low versus MPPE1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPPE1→partner) and Y-score (partner→MPPE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Protein localization to phagophore assembly site →	+0.079	+0.910	<.001	<.001	3	32
SCLC	GPI anchor metabolic process →	+0.079	+0.719	<.001	<.001	3	31
THYM	Golgi to plasma membrane transport →	+0.076	+0.843	<.001	<.001	3	31
THYM	Regulation of lysosome organization →	+0.072	+0.783	<.001	<.001	3	31
THYM	Vesicle-mediated transport between endosomal compartments →	+0.066	+0.788	<.001	<.001	3	30
SCLC	Rescue of stalled ribosome →	+0.078	+0.646	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Protein localization to phagophore assembly site by MPPE1 expression — THYM

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