MPP7

Across TCGA cell cohorts, MPP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,464 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MPP7-associated GO terms across cancer lineages are Protein localization to adherens junction, Establishment of epithelial cell apical/basal polarity, and Desmosome organization. Each is linked with MPP7 in more than 13 cancer types. Because this analysis shows association rather than direction, both MPP7-to-partner and partner-to-MPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to adherens junction grouped by MPP7-low versus MPP7-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP7→partner) and Y-score (partner→MPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein localization to adherens junction →	-0.154	-1.068	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Establishment of epithelial cell apical/basal polarity →	-0.217	-1.633	<.001	<.001	3	8
OVARY	Desmosome organization →	+0.347	+1.894	<.001	<.001	3	8
OVARY	Cellular respiration →	+0.104	+1.493	<.001	<.001	3	7
OVARY	Aerobic respiration →	+0.109	+1.653	<.001	<.001	3	7
CNS	Negative regulation of CD4-positive, alpha-beta T cell differentiation →	-0.110	-0.998	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,464 associations by consensus.

Protein localization to adherens junction by MPP7 expression — BLOOD_Leukemia

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