MPP6

Across TCGA patient cohorts, MPP6 protein abundance is significantly associated with the RNA expression of many other genes, with 13,459 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MPP6-associated genes across cancer lineages are SUMO2P14, NAP1L2, and ATP6V1E2. Each is linked with MPP6 in more than 6 cancer types. Because this analysis shows association rather than direction, both MPP6-to-partner and partner-to-MPP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPP6 versus SUMO2P14 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP6→partner) and Y-score (partner→MPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SUMO2P14 →	+0.916	+0.429	<.001	<.001	3	7
LSCC	NAP1L2 →	+0.996	+0.366	<.001	.001	3	5
LSCC	ATP6V1E2 →	+0.648	+0.479	<.001	<.001	3	5
BRCA	MAP7D3 →	+0.704	+0.519	<.001	<.001	3	5
UCEC	PCYT1B →	+0.900	+0.413	.005	.001	3	4
OV	WDR59 →	+0.568	+0.475	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,459 associations by consensus.

MPP6 vs SUMO2P14 — UCEC

Explore this scatter interactively →