MPP6

Across TCGA cell cohorts, MPP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,791 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MPP6-associated GO terms across cancer lineages are DNA-templated transcription initiation, Transcription by RNA polymerase I, and rRNA processing. Each is linked with MPP6 in more than 16 cancer types. Because this analysis shows association rather than direction, both MPP6-to-partner and partner-to-MPP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by MPP6-low versus MPP6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP6→partner) and Y-score (partner→MPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.089	+1.741	.001	<.001	3	17
OESOPHAGUS	Transcription by RNA polymerase I →	+0.141	+2.078	.001	.001	3	17
OESOPHAGUS	rRNA processing →	+0.108	+1.266	<.001	.002	3	16
BLOOD_Myeloma	Ribosome biogenesis →	+0.107	+1.350	<.001	<.001	3	16
SOFT_TISSUE	DNA-templated transcription elongation →	+0.087	+1.040	<.001	<.001	3	15
OESOPHAGUS	Nucleocytoplasmic transport →	+0.079	+1.229	.003	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,791 associations by consensus.

DNA-templated transcription initiation by MPP6 expression — BONE

Explore this box plot interactively →