MPP5

Across TCGA patient cohorts, MPP5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,860 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MPP5-associated genes across cancer lineages are EXD2, MED6, and MNAT1. Each is linked with MPP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both MPP5-to-partner and partner-to-MPP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPP5 versus EXD2 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP5→partner) and Y-score (partner→MPP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EXD2 →	+0.482	+0.225	<.001	<.001	3	7
LUAD	MED6 →	+0.460	+0.243	<.001	<.001	3	7
GBM	MNAT1 →	+0.482	+0.265	<.001	<.001	3	7
UCEC	ZC3H14 →	+0.414	+0.293	.003	<.001	3	6
HNSC	IL2RG →	-1.024	-0.203	<.001	.001	3	6
UCEC	GOLGA5 →	+0.727	+0.266	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,860 associations by consensus.

MPP5 vs EXD2 — GBM

Explore this scatter interactively →