MPP5

Across TCGA cell cohorts, MPP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,855 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPP5-associated GO terms across cancer lineages are Regulation of mitotic cytokinesis, Positive regulation of cytokinesis, and Centriole replication. Each is linked with MPP5 in more than 13 cancer types. Because this analysis shows association rather than direction, both MPP5-to-partner and partner-to-MPP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic cytokinesis grouped by MPP5-low versus MPP5-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP5→partner) and Y-score (partner→MPP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of mitotic cytokinesis →	+0.108	+0.901	<.001	<.001	3	14
BREAST	Positive regulation of cytokinesis →	+0.112	+0.959	.005	<.001	3	14
BLOOD_Leukemia	Centriole replication →	+0.086	+0.677	<.001	<.001	3	13
OVARY	Spliceosome-depend formation of circular RNA →	+0.162	+0.930	<.001	<.001	3	13
CNS	Regulation of hippo signaling →	+0.077	+0.965	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of cell cycle →	+0.056	+0.716	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

Regulation of mitotic cytokinesis by MPP5 expression — CNS

Explore this box plot interactively →