MPP2

Across TCGA cell cohorts, MPP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,637 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MPP2-associated GO terms across cancer lineages are Protein-DNA complex organization, Epigenetic regulation of gene expression, and Transcription initiation at RNA polymerase II promoter. Each is linked with MPP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both MPP2-to-partner and partner-to-MPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by MPP2-low versus MPP2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP2→partner) and Y-score (partner→MPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein-DNA complex organization →	+0.071	+1.287	<.001	<.001	3	19
STOMACH	Epigenetic regulation of gene expression →	+0.087	+1.987	<.001	<.001	3	18
BREAST	Transcription initiation at RNA polymerase II promoter →	+0.069	+1.602	<.001	<.001	3	18
STOMACH	Negative regulation of gene expression, epigenetic →	+0.095	+2.086	<.001	<.001	3	17
BONE	Regulation of DNA repair →	+0.074	+0.991	.004	.004	3	17
OESOPHAGUS	RNA localization →	+0.140	+1.485	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,637 associations by consensus.

Protein-DNA complex organization by MPP2 expression — KIDNEY

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