MPP1

Across TCGA cell cohorts, MPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,933 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MPP1-associated GO terms across cancer lineages are PML body organization, Aorta smooth muscle tissue morphogenesis, and Positive regulation of cell-substrate junction organization. Each is linked with MPP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MPP1-to-partner and partner-to-MPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by MPP1-low versus MPP1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP1→partner) and Y-score (partner→MPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PML body organization →	+0.180	+1.659	<.001	<.001	3	12
URINARY_TRACT	Aorta smooth muscle tissue morphogenesis →	+1.715	+2.347	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of cell-substrate junction organization →	+0.153	+2.574	<.001	<.001	3	10
PANCREAS	Negative regulation of potassium ion transmembrane transporter activity →	-1.137	-2.444	.001	<.001	3	10
BREAST	Positive regulation of supramolecular fiber organization →	+0.079	+1.869	<.001	<.001	3	10
PANCREAS	Negative regulation of voltage-gated potassium channel activity →	-1.137	-2.444	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,933 associations by consensus.

PML body organization by MPP1 expression — LUNG_NSCLC_LUAD

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