MPLKIP

Across TCGA patient cohorts, MPLKIP protein abundance is significantly associated with the protein abundance of many other proteins, with 19,484 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MPLKIP-associated proteins across cancer lineages are PRRC2A, DBR1, and SART1. Each is linked with MPLKIP in more than 7 cancer types. Because this analysis shows association rather than direction, both MPLKIP-to-partner and partner-to-MPLKIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPLKIP versus PRRC2A in HNSC, with a Pearson correlation of 0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPLKIP→partner) and Y-score (partner→MPLKIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRRC2A →	+0.250	+0.377	<.001	<.001	3	8
LSCC	DBR1 →	+0.368	+0.520	<.001	<.001	3	8
GBM	SART1 →	+0.236	+0.350	<.001	<.001	3	7
LSCC	WDR33 →	+0.223	+0.492	<.001	<.001	3	7
GBM	PHF3 →	+0.225	+0.389	<.001	.002	3	7
BRCA	PLRG1 →	+0.276	+0.659	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,484 associations by consensus.

MPLKIP vs PRRC2A — HNSC

Explore this scatter interactively →