Across TCGA patient cohorts, MPIG6B protein abundance is significantly associated with the RNA expression of many other genes, with 1,317 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MPIG6B-associated genes across cancer lineages are PF4, HBA1, and ZFP36. Each is linked with MPIG6B in more than 2 cancer types. Because this analysis shows association rather than direction, both MPIG6B-to-partner and partner-to-MPIG6B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPIG6B→partner) and Y-score (partner→MPIG6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PF4 →	+1.029	+0.624	<.001	<.001	3	3
GBM	HBA1 →	+1.130	+0.562	<.001	<.001	3	3
UCEC	ZFP36 →	+1.494	+1.272	.007	.007	2	3
UCEC	PPBP →	+1.718	+1.274	.004	.002	3	2
GBM	TREML2 →	+0.485	+0.556	<.001	<.001	3	2
LSCC	IL1RL1 →	+1.296	+0.755	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,317 associations by consensus.

Exploration

MPIG6B survival (RNA) · tumor vs normal (RNA) · all MPIG6B data types