Across TCGA patient cohorts, MPHOSPH8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MPHOSPH8-associated genes across cancer lineages are TMED2-DT, DCP1A, and ATRIP. Each is linked with MPHOSPH8 in more than 4 cancer types. Because this analysis shows association rather than direction, both MPHOSPH8-to-partner and partner-to-MPHOSPH8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPHOSPH8→partner) and Y-score (partner→MPHOSPH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMED2-DT →	+0.390	+0.223	<.001	<.001	3	5
HNSC	DCP1A →	+0.343	+0.118	.006	<.001	3	5
BRCA	ATRIP →	+0.455	+0.177	.001	<.001	3	5
GBM	SUPT20H →	+0.517	+0.289	<.001	<.001	3	4
HNSC	MBTD1 →	+0.665	+0.158	.002	<.001	2	5
GBM	KANSL1 →	+0.413	+0.231	.006	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,380 associations by consensus.

Exploration

MPHOSPH8 survival (RNA) · tumor vs normal (RNA) · all MPHOSPH8 data types