Across TCGA cell cohorts, MPHOSPH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,633 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MPHOSPH8-associated GO terms across cancer lineages are Positive regulation of cytoplasmic mRNA processing body assembly, Regulation of alternative mRNA splicing, via spliceosome, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with MPHOSPH8 in more than 13 cancer types. Because this analysis shows association rather than direction, both MPHOSPH8-to-partner and partner-to-MPHOSPH8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPHOSPH8→partner) and Y-score (partner→MPHOSPH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.113	+1.317	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.103	+1.029	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of hematopoietic stem cell differentiation →	+0.172	+0.784	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.091	+1.080	<.001	<.001	3	13
BONE	RNA catabolic process →	+0.079	+0.791	<.001	<.001	3	13
OESOPHAGUS	Cytosolic transport →	+0.086	+1.114	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,633 associations by consensus.

Exploration

MPHOSPH8 survival (RNA) · tumor vs normal (RNA) · all MPHOSPH8 data types