MPHOSPH6P1

Across TCGA pan-cancer cohorts, MPHOSPH6P1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MPHOSPH6P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MPHOSPH6P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MPHOSPH6P1 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

HNSC, COAD, and STAD are the cancer types where MPHOSPH6P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MPHOSPH6P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.134	<.001	8	view →
COAD	All	II,III,IV	+0.232	<.001	6	view →
STAD	Male	II,III,IV	+0.330	.025	4	view →
BLCA	All	All	+0.317	.024	2	view →
BRCA	All	III,IV	−0.236	.008	2	view →
LUAD	Male	III,IV	−0.266	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MPHOSPH6P1–HNSC

Open the HNSC breakdown →