MPHOSPH6

Across TCGA pan-cancer cohorts, MPHOSPH6 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MPHOSPH6 data layer compared with 21 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MPHOSPH6 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MPHOSPH6 expression acts as an unfavorable survival marker.

LUAD, SKCM, and BLCA are the cancer types where MPHOSPH6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.178	0.813	<.001	12	view →
SKCM	DFS	Median	All	0.198	0.728	.015	12	view →
BLCA	OS	Median	IV	0.183	0.598	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MPHOSPH6–LUAD (DFS)

Open the LUAD breakdown →