MPHOSPH6

Across TCGA pan-cancer cohorts, MPHOSPH6 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MPHOSPH6 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MPHOSPH6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MPHOSPH6 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where MPHOSPH6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.449	.010	16	view →
LUAD	OS	Median	II,III,IV	0.844	0.468	.024	13	view →
LSCC	OS	Tertile	II,III,IV	0.945	0.541	.003	12	view →
CCRCC	DFS	Quartile	III,IV	0.811	1.000	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MPHOSPH6–UCEC (OS)

Open the UCEC breakdown →